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Semax vs Selank: A Research Peptide Comparison
Semax and Selank are two synthetic peptides developed in Russian neuropeptide research, and they are frequently studied together. They are different molecules with different parent origins. This comparison summarises how they differ — strictly as research chemicals.
Quick comparison
| Semax | Selank | |
|---|---|---|
| Parent molecule | ACTH(4-10) fragment | Tuftsin analog |
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro | Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| Research area | Neurotrophic / cognitive models | Anxiolytic / neuroimmune models |
| Class | Melanocortin-derived peptide | Immunomodulatory-peptide analog |
Different origins
The core difference is the parent molecule. Semax is derived from a fragment of ACTH (adrenocorticotropic hormone), specifically the ACTH(4-10) region, and is studied in neurotrophic and cognition-model research. Selank is a synthetic analog of the endogenous immunomodulatory peptide tuftsin, and is studied more in anxiolytic-model and neuroimmune research. Both carry a stabilising Pro-Gly-Pro extension.
What each is studied for
- Semax — BDNF/neurotrophic signaling and cognition-model endpoints in research systems.
- Selank — GABA/serotonin-system interactions and neuroimmune endpoints in model systems.
Sourcing verified material
Both should ship with a lot-specific third-party COA (HPLC purity + mass-spec identity), from US synthesis, with cold-chain shipping.
FAQ
What is the difference between Semax and Selank?
Semax is derived from the ACTH(4-10) fragment and is studied in neurotrophic and cognition-model research; Selank is a tuftsin analog studied more in anxiolytic-model and neuroimmune research. They are different molecules with different parent origins.